Starring Will Smith, Jared Leto and Margot Robbie as a band of deadly criminals recruited to execute dangerous black-ops missions, the film has an average critical score of 4.7 out of 10 on the reviews aggregation website Rotten Tomatoes. (READ: 'Suicide Squad' cast defends movie after bad reviews: It's for the fans)
The bawdy comedy Bad Moms starring Mila Kunis, Kristin Bell and Kathryn Hahn as overworked and under-appreciated mothers who ditch responsibility for indulgence drew in $14.2 million to nab third place.
The Secret Life of Pets took fourth with $11.6 million, bringing one of the year's biggest hits to an impressive $319.6 million total.
Paramount's Star Trek Beyond – the latest installment in the 50-year-old franchise – dropped to fifth with $10.2 million.
Rounding out the top 10 films of the weekend were: