PARIS, France – One in 10 diabetics with coronavirus dies within 7 days of hospital admission, according to a study of more than 1,300 patients published Friday, May 29, in the journal Diabetologia.
Two-thirds of the patients were men, and the average age across both sexes was 70, the study found.
"The presence of diabetic complications and increased age increase the risk of death," the researchers said in a statement.
"Increased BMI" – body mass index, a ratio of height to weight – "is associated with both increased risk of needing mechanical ventilation and with increased risk of death," they said.
Worse blood sugar control in and of itself, however, did not seem to impact a patient's outcome.
So-called microvascular complications – affecting the eyes, kidney and nerves – were found in nearly half of the patients, who were admitted to 53 French hospitals from March 10 to March 31.
Problems related to larger arteries in the heart, brain and legs were reported in more than 40% of the patients.
The presence of either type of complication doubled the risk of death by the seventh day of hospitalization.
Patients over 75 years old were 14 times more likely to die than those 55 or younger.
By the seventh day of hospitalization, a fifth of patients had been intubated on ventilators, and a tenth had died. Nearly a quarter of patients had been discharged home by this point.
The study confirmed that insulin and other treatments modifying blood sugar were not a risk factor for severe forms of COVID-19, and should be continued for persons with diabetes.
Other significant risk factors included heart disease, high blood pressure, and a history of lung disease.
The number of confirmed cases of COVID-19 worldwide is approaching 6 million, with the actual number thought to be an order of magnitude higher.
More than 354,000 deaths have been registered.
In a grim signal to other countries hoping to exit lockdown, South Korea reimposed social distancing rules this week after a spike in new cases. – Rappler.com