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Lopez is the daughter of the late ABS-CBN chairman emeritus Eugenio Lopez Jr.
The television channel is widely perceived by Duterte supporters to be anti-Duterte, especially after it broadcast an unflattering political advertisement paid for by Senator Antonio Trillanes IV.
She is known to vehemently oppose mining activities and coal-fired powerplants and has campaigned against coal mining in Semirara Island, Antique. She also spearheaded her foundation’s efforts to clean up the Pasig River and has supported eco-tourism efforts in various parts of the country.